Medicinal Chemistry
8 Invention Families 11 Patent Families 55 Patents
(As of December 16, 2022)
020 Azaphenylene Mediated Aβ Disaggregation for Alzheimer’s Disease (2012-09-28)
036 Dihydro-6-Azaphenalene Derivatives for the Treatment of CNS, Oncological Diseases and Related Disorders
John C. Warner, Dieu Nguyen, Jeffery A. Gladding, Srinivasa R. Cheruku, Jean R. Loebelenz, James J. Norman, Sambaiah Thota, John W. Lee,
Craig Rosenfeld
110 US 10,047,089 Granted 2018-08-14, Published 2014-04-03, Filed 2013-09-27
111 WO 2014/052906 Published 2014-04-03, Filed 2013-09-27
112 AU 2013/323198 Granted 2018-03-29, Published 2015-04-09, Filed 2013-09-27
113 BR 11/2015/007095 Published 2017-07-04, Filed 2013-09-27
114 CA 2886749 Published 2014-04-03, Filed 2013-09-27
115 CN 104994853 Granted 2018-11-30, Published 2015-10-21, Filed 2013-09-27
116 EP2900239 Granted 2019-03-20, Published 2015-08-05, Filed 2013-09-27
117 IL 237912 Published 2015-05-31, Filed 2015-03-23
118 IN 1121/KOLNP/2015 Granted 2021-02-26, Published 2016-01-08, Filed 2015-04-22
119 JP 6345674 Granted 2018-06-20, Published 2015-11-02, Filed 2013-09-27
120 KR 2015/0060775 Published 2015-06-03, Filed 2013-09-27
024 Pyrido[2,3-d]pyridazine Derivatives (Rilyazine) Anticancer Cytostats (2013-09-05)
041 Preparation of Rilyazine derivatives useful in treatment of cancer
John C. Warner, Jeffery A. Gladding, Thomas W. Gero and Srinivasa R. Cheruku
128 US 9,394,299 Granted 2016-07-19, Published 2015-03-05, Filed 2014-08-29
129 WO 2015/034785 Published 2015-03-12, Filed 2014-08-29
130 AU 2014/315422 Published 2015/03/12, Filed 2014-08-29
131 EP 3041840 Granted 2018-02-28, Published 2016-07-13, Filed 2014-08-29
026 Mechanochemical NCD Therapy for ALS and other CNS Diseases (2013-11-11)
044 Metal Complexes and Methods of Treatment
John C. Warner, Srinivasa R. Cheruku, Anitha Hari and James J. Norman
145 US 11,266,686 Granted 2022-03-08, Published 2016-09-22, Filed 2014-11-10
146 WO 2015/070177 Published 2015-05-14, Filed 2014-11-10
147 AU 2014/346476 Granted 2019-01-24, Published 2016-06-23, Filed 2014-11-10
148 CA 2930290 Published 2015-05-14, Filed 2014-11-10
149 CN 105899519 Granted 2021-11-09, Published 2016-08-24, Filed 2014-11-10
150 EP 3068762 Granted 2019-12-25, Published 2016-09-21, Filed 2014-11-10
151 ES 2778038 Granted 2020-08-07, Published 2020-08-07, Filed 2014-11-10
152 IL 245593 Published 2016-06-30, Filed 2016-05-10
153 IN 362647 Granted 2021-03-23, Published 2016-08-26, Filed 2016-06-10
154 JP 6619348 Granted 2019-12-11, Published 2016-12-28, Filed 2014-11-10
029 Synthesis of N-Acetyl-L-Cysteinamide (2014-03-28)
049 Method for the Preparation of N-Acetyl-L-Cysteinamide from N-Acetyl-L-Cysteine
John C. Warner, Srinivasa Cheruku, Sambaiah Thota and John W. Lee
171 US 9,763,902 Granted 2017-09-19, Published 2017-06-29, Filed 2015-03-27
172 WO 2015/148880 Published 2015-10-01, Filed 2015-03-27
173 EP 3122342 Granted 2020-0923, Published 2017-02-01, Filed 2015-03-27
050 Method for the Preparation of N-Acetyl-L-Cysteinamide from N-Acetyl-L-Cysteine, Continuation
John C. Warner, Srinivasa Cheruku, Sambaiah Thota and John W. Lee
174 US 9,889,103 Granted 2018-02-13, Published 2017-12-28, Filed 2017-09-06
033 Dipyridyl Thiosemicarbazone Anti-Cancer Agents (2015-09-25)
061 Preparation of Dipyridyl Thiosemicarbazones as Anticancer Agents
John C. Warner, Jeffery A. Gladding and Srinivasa R. Cheruku
206 US 62/234,198. Filed 2015-09-29. Unpublished
207 WO 2017/058748 Published 2017-04-06, Filed 2016-09-27
034 2-Phenyl Benzofuran Derivatives for Aβ and Amylin Disaggregation (2015-11-11)
062 Preparation of 2-Phenylbenzofuran Derivatives for the Treatment of Central Nervous System Disorders and Other Disorders
John C. Warner, Srinivasa R. Cheruku and Jeffery A. Gladding
208 US 10,590,100 Granted 2020-03-17, Published 2018-12-06, Filed 2016-11-10
209 WO 2017/083488 Published 2017-05-18, Filed 2016-11-10
210 AU 2016/353004 Granted 2020-11-05, Published 2018-06-14, Filed 2016-11-10
211 CA 3005212 Published 2017-05-18, Filed 2016-11-10
212 CN 10869901 Granted 2022-05-10, Published 2018-10-23, Filed 2016-11-10
213 EP 3374354 Granted 2022-09-28, Published 2018-09-19, Filed 2016-11-10
214 IL 259674 Published 2018-07-31, Filed 2018-05-29
215 JP 6908805 Granted 2021-07-28, Published 2019-01-24, Filed 2016-11-10
063 Preparation of stilbene derivatives for use as central nervous system agents
John C. Warner
216 US 11,286,233 Granted 2022-03-29, Published 2021-04-22, Filed 2018-05-08
217 WO 2018/208709 Published 2018-11-15, Filed 2018-05-08
218 EP 3621945 Published 2021-03-03, Filed 2018-05-08
043 NCDs of HDAC Inhibitors (2017-06-01)
080 Noncovalent Derivatives of Histone Deacetylase Inhibitors and Methods of Treatment
Carmen M. Baldino, Laura Muollo, and John C. Warner
309 US 62/516,585. Filed 2017-06-01. Unpublished
310 WO 2018/222572 Published 2018-12-06, Filed 2018-05-29
046 Heterobicyclic Compounds for Ferroptosis Related Diseases (2017-12-01)
083 Preparation of Heterobicyclic Aromatic Derivatives for the Treatment of Ferroptosis-Related Disorders
John C. Warner, Carmen Baldino, Laura Muollo and Craig Rosenfeld
316 US 62/593,607. Filed 2017-01-12. Unpublished
317 WO 2019/106434 Published 2019-06-06, Filed 2018-11-30
084 Heteroaromatic and Heterobicyclic Aromatic Derivatives for the Treatment of Ferroptosis- Related Disorders
John Warner, Carmen Baldino, Laura Muollo, John Lee, Srinivasa Cheruku, Rowan Walker, James Siedlecki, John Proudfoot, Shawn Johnstone,
Mehdi Numa and Craig Rosenfeld
318 US 2022/0144826 Published 2019-05-12, Filed 2020-03-10
319 WO 2020/185738 Published 2020-09-17, Filed 2020-03-10
320 AU 2020/234788 Published 2021-10-28, Filed 2020-03-10
321 BR 112021017831 Published 2021-11-30 Filed 2020-03-10
322 CA 3133070 Published 2020-09-17, Filed 2020-03-10
323 CN 113631535 Published 2021-09-11, Filed 2020-03-10
324 EP 3938340 Published 2022-01-19, Filed 2020-03-10
325 IL 286180 Published 2021-10-32, Filed 2021-09-05
326 IN 2021/37046034 Published 2022-01-14, Filed 2021-10-08
327 JP 2022/523860 Published 2022-04-26, Filed 2020-03-10
328 KR 10 2021/0137134 Published 2021-11-17, Filed 2020-03-10
329 MX 2021/010888. Filed 2020-03-10.